Kohno K, Yamaguchi T, Takahashi T
Tohoku J Exp Med. 1979 Feb;127(2):183-8. doi: 10.1620/tjem.127.183.
Intralymphatic inoculation of rat ascites hepatoma AH 130 was carried out to elucidate the function of the regional lymph node as a barrier against tumor spread. Tumor cells reaching regional lymph nodes decreased in number 48 to 72 hr after inoculation. Ten percent of tumor cells injected into lymphatic vessels appeared in the thoracic duct within 3 hr after injection. Bioassay tests revealed that transnodal tumor cells were viable in the thoracic duct.
为阐明区域淋巴结作为肿瘤扩散屏障的功能，对大鼠腹水型肝癌AH 130进行了淋巴管内接种。接种后48至72小时，到达区域淋巴结的肿瘤细胞数量减少。注入淋巴管的肿瘤细胞中有10%在注射后3小时内出现在胸导管中。生物测定试验表明，经淋巴结的肿瘤细胞在胸导管中具有活力。
