Sherman D M, Trach V M
Klin Khir (1962). 1994(9):38-41.
In acute experiment on 95 adult rabbits it was determined that during the subdivided blood exfusion from femoral artery in the volume of (16 + 1) ml/kg the reversible hemorrhagic shock occurs and the animals survive without the hemorrhage compensation. The increase of hemorrhage volume up to (23 + 3) ml/kg leads to lethal hemorrhagic shock. The heparinized blood reinfusion in the early period promotes the survival of the whole of animals, in the late period it promotes trustworthy their life span increase. Under the influence of dalargin intravenous infusion in the dose of 0.1 mg/kg after the blood reinfusion in the late period of shock all the animals survived. Intravenous infusion of dalargin is expedient for the increase of the transfusion therapy effectiveness in the late period of hemorrhagic shock.
在对95只成年兔子进行的急性实验中确定，当从股动脉以(16 + 1)毫升/千克的量进行分次放血时，会发生可逆性失血性休克，且动物在没有出血代偿的情况下存活。出血量增加至(23 + 3)毫升/千克会导致致命性失血性休克。早期进行肝素化血液回输可促进所有动物存活，晚期进行则可显著延长其寿命。在休克晚期血液回输后，以0.1毫克/千克的剂量静脉输注达拉丁，所有动物均存活。静脉输注达拉丁有利于提高失血性休克晚期输血治疗的效果。
