Liu G, Orihashi K, Shikata H, Murakami H, Fukunaga S, Sueda T, Matsuura Y
First Department of Surgery, Hiroshima University School of Medicine, Japan.
Panminerva Med. 1994 Dec;36(4):160-7.
The effects of passive (no pump) and active (using centrifugal pump) shunting on hemodynamics and metabolisms during cross-clamping of the descending thoracic aorta were compared in mongrel dogs. In Group I (control), the aorta was cross-clamped for 2 hours without shunting; in Group II (passive), a temporary shunt was placed between the left common carotid and left femoral arteries during cross-clamping; and in Group III (active), left heart by-pass, matching flow to that in group II, was performed. Hemodynamic and metabolic parameters were recorded prior to cross-clamping and following every 30 min for 4 hours. All animals in Group I suffered from hemodynamic instability, metabolic abnormal and neurologic injury and died within 12 hours. Hemodynamic changes were unstable in Group III than II, and three dogs in Group III, but none in Group II, suffered from neurologic injury. Metabolic changes between Group II and III were not significant. We conclude that passive shunting is superior to active shunting for aortic by-pass.
在杂种犬中比较了被动（无泵）分流和主动（使用离心泵）分流对胸降主动脉交叉钳夹期间血流动力学和代谢的影响。I组（对照组）在无分流情况下将主动脉交叉钳夹2小时；II组（被动组）在交叉钳夹期间于左颈总动脉和左股动脉之间放置临时分流；III组（主动组）进行左心旁路，使流量与II组匹配。在交叉钳夹前以及之后每30分钟记录4小时的血流动力学和代谢参数。I组所有动物均出现血流动力学不稳定、代谢异常和神经损伤，并在12小时内死亡。III组的血流动力学变化比II组不稳定，III组有3只犬出现神经损伤，而II组无。II组和III组之间的代谢变化不显著。我们得出结论，在主动脉旁路中，被动分流优于主动分流。
