Tappin D M, Johnstone F D, Smith R, Girdwood R W, Follett E A, Davidson C F
Department of Child Health, Royal Hospital for Sick Children, Glasgow.
Scott Med J. 1995 Feb;40(1):12-4. doi: 10.1177/003693309504000105.
In Scotland since January 1990, unlinked anonymous testing of Guthrie cards has documented maternal HIV-1 antibody in neonatal blood. District postcode and quarter year of birth determined prevalence and spread of infection. The Fujirebio particle agglutination assay screened for HIV-1 antibody, with confirmation by ELISA and full western blotting. Births to known HIV infected women were reported to the Royal College of Obstetricians and Gynaecologists. 0.3/1000 childbearing women were infected with HIV-1 with no significant increase from 1990 to 1992. Spread of infection from 11 to 26 districts has occurred. In 1990, 74%(14/19) of HIV positive deliveries were known to obstetricians falling to 33%(7/21) in 1992. Spread of HIV-1 infection has occurred to mothers who live outside closely defined areas and who do not belong to recognised high risk groups. In Scotland, two thirds of mothers and their infants will not receive early prophylactic care for their HIV disease.
自1990年1月起在苏格兰，对古思里卡片进行不关联匿名检测已记录到新生儿血液中的母体HIV-1抗体。地区邮政编码和出生季度确定了感染的患病率和传播情况。富士瑞必欧颗粒凝集试验筛查HIV-1抗体，通过酶联免疫吸附测定和完整的蛋白质印迹法进行确认。已知感染HIV的妇女所生婴儿会上报给皇家妇产科学院。每1000名育龄妇女中有0.3人感染HIV-1，1990年至1992年期间无显著增加。感染已传播至11至26个地区。1990年，74%（14/19）的HIV阳性分娩为产科医生所知，1992年降至33%（7/21）。HIV-1感染已传播至居住在严格界定区域之外且不属于公认高危人群的母亲。在苏格兰，三分之二的母亲及其婴儿不会因其HIV疾病而接受早期预防性护理。
