Tappin D M, Girdwood R W, Follett E A, Kennedy R, Brown A J, Cockburn F
Department of Child Health, Royal Hospital for Sick Children, Glasgow.
Scott Med J. 1993 Feb;38(1):16-7. doi: 10.1177/003693309303800106.
In January 1990, unlinked anonymous testing of Guthrie cards for HIV antibody commenced in Scotland. Ethics Committee approval allowed testing of 99.6% of Scottish births. Twenty-one mothers spontaneously refused to allow testing of their baby's blood. Samples were coded by district postcodes. For 1990 through 1991, eluates of 132,531 dried blood spots were initially tested for HIV-1 antibody with the Fujirebio technique. Of the 49 positive samples 38 were confirmed to be positive by enzyme-linked immunosorbent assay and western blot (seroprevalence 0.3 per 1000). Thirty-five of 38 samples came from large metropolitan areas in Scotland. Prevalences were 2.0 per 1000 for Edinburgh city, 0.7 per 1000 for Dundee and Aberdeen, 0.15 per 1000 for Glasgow and 0.05 per thousand for all other areas in Scotland. Recent spread of HIV infection to Aberdeen may have occurred. These figures do not support an overall increase of HIV infection in childbearing women in Scotland.
1990年1月，苏格兰开始对用于检测HIV抗体的古思里卡片进行非关联匿名检测。伦理委员会批准后，对99.6%的苏格兰出生婴儿进行检测。21位母亲自发拒绝检测其婴儿的血液。样本按地区邮政编码编码。1990年至1991年，首先采用富士瑞必欧技术对132,531份干血斑洗脱液进行HIV-1抗体检测。49份阳性样本中，38份经酶联免疫吸附测定和免疫印迹法确认为阳性（血清阳性率为每1000人中有0.3例）。38份样本中的35份来自苏格兰的大城市地区。爱丁堡市的患病率为每1000人中有2.0例，邓迪和阿伯丁为每1000人中有0.7例，格拉斯哥为每1000人中有0.15例，苏格兰其他地区为每千人中有0.05例。HIV感染可能最近已传播到阿伯丁。这些数据并不支持苏格兰育龄妇女中HIV感染率总体上升的情况。
