Kolesnyk M O, Lapchyns'ka I I, Bielyts'ka H O
Lik Sprava. 1994 Sep-Dec(9-12):145-8.
The paper treats of the mechanisms of antiaggregant and vasoactive effect of curantyl (C) in chronic glomerulonephritis (ChGN). As many as 85 ChGN C-treated patients were examined; positive treatment effect was seen in 35.5%, negative one in 12.9% of the patients; no effect in 25.8%. It has been ascertained that in some instances prognostically unfavourable forms of ChGN do respond to C treatment. Efficacy of C therapy is predictable from the baseline 24 h proteinuria and decrease in urinary excretion of products of fibrinogen/fibrin degradation during the first week of treatment.
本文探讨了库兰特（C）对慢性肾小球肾炎（ChGN）的抗聚集和血管活性作用机制。共检查了85例接受C治疗的ChGN患者；35.5%的患者治疗效果为阳性，12.9%为阴性；25.8%无效果。已确定在某些情况下，预后不良的ChGN形式确实对C治疗有反应。C治疗的疗效可根据基线24小时蛋白尿以及治疗第一周纤维蛋白原/纤维蛋白降解产物尿排泄量的减少来预测。
