Kolesnyk M O, Lapchyns'ka I I
Lik Sprava. 1996 Jan-Feb(1-2):135-7.
Both short-term and long-term effectiveness of xantinole nicotinate as well as trentale and combinations thereof with dipyridamole has been demonstrated in patients with chronic glomerulonephritis presenting with grade 1 chronic renal insufficiency, which fact can be accounted for by their vasoactive and antiaggregant actions. Particular regimens have been developed to treat the medical condition in question with the above drug preparations, comparative evaluation was done of their effects on the clinical course of the illness as well as on the effective renal plasma flow, concentration of nitrogenous remainder in blood and urine, concentration of medium size molecules in blood. It is advisable that antiaggregants be administered long term (from several months to several years).
烟酸占替诺以及曲克芦丁及其与双嘧达莫的组合在患有1级慢性肾功能不全的慢性肾小球肾炎患者中已证明具有短期和长期疗效，这一事实可归因于它们的血管活性和抗聚集作用。已制定了特定方案用上述药物制剂治疗相关病症，对它们对疾病临床进程以及有效肾血浆流量、血液和尿液中含氮残余物浓度、血液中中等大小分子浓度的影响进行了比较评估。建议长期（从数月到数年）服用抗聚集剂。
