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[库兰特利对慢性肾小球肾炎患者的血管活性作用]

[The vasoactive action of kurantil in patients with chronic glomerulonephritis].

作者信息

Kolesnyk M O, Lapchyns'ka I I, Pryshchepa P P

出版信息

Lik Sprava. 1995 Mar-Apr(3-4):162-4.

PMID:8819955
Abstract

The immediate positive result of 3-4 weeks' course of treatment with curantyl (C) of patients with chronic glomerulonephritis (ChGN) is due to both vasoactive and antiaggregant action of the preparation. The negative immediate result of C treatment appear to be associated with <>. C was found to be usefull in treatment of ChGN patients presenting with predominance of fibroplastic changes in the kydneys, those with arterial hypertension, grade I ChGN. Analysis of late results of treatment 1.5-2 years after C withdrawal revealed improvement in health status in 22.5% and slowing down ChGN progression in 15% of patients compared to the control group.

摘要

用库兰特(C)对慢性肾小球肾炎(ChGN)患者进行3至4周疗程治疗的即时积极效果,归因于该制剂的血管活性和抗聚集作用。C治疗的即时负面效果似乎与“窃血综合征”有关。已发现C对肾内以纤维增生性改变为主的ChGN患者、患有动脉高血压的ChGN患者(I级)的治疗有效。在停用C 1.5至2年后对治疗的远期效果进行分析发现,与对照组相比,22.5%的患者健康状况有所改善,15%的患者ChGN进展减缓。

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