获得性大疱性表皮松解症后系统性红斑狼疮的致命性血管受累

Fatal vascular involvement in systemic lupus erythematosus following epidermolysis bullosa acquisita.

作者信息

Yoon J, Moon T K, Lee K H, Kim S C

机构信息

Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Acta Derm Venereol. 1995 Mar;75(2):143-6. doi: 10.2340/0001555575143146.

DOI:10.2340/0001555575143146

PMID:7604645

Abstract

Epidermolysis bullosa acquisita may be associated with various systemic diseases, including systemic lupus erythematosus. We describe the clinical and immunological findings in a 38-year-old women with epidermolysis bullosa acquisita and systemic lupus erythematosus. The epidermolysis bullosa acquisita preceded a dramatic flare of systemic lupus erythematosus and fatal cerebral vasculitis. If serologic evidence of lupus erythematosus develops during the course of epidermolysis bullosa acquisita, a thorough investigation is warranted to rule out potentially life-threatening systemic lupus erythematosus.

摘要

获得性大疱性表皮松解症可能与多种全身性疾病相关，包括系统性红斑狼疮。我们描述了一名38岁患有获得性大疱性表皮松解症和系统性红斑狼疮的女性的临床和免疫学表现。获得性大疱性表皮松解症先于系统性红斑狼疮的剧烈发作和致命性脑血管炎出现。如果在获得性大疱性表皮松解症病程中出现红斑狼疮的血清学证据，则有必要进行全面检查以排除可能危及生命的系统性红斑狼疮。