Bergh C, Josefsson B, Nilsson L, Hamberger L
Department of Obstetrics and Gynecology, Sahlgrenska Hospital, University of Göteborg, Sweden.
Acta Obstet Gynecol Scand. 1995 Jul;74(6):446-50. doi: 10.3109/00016349509024407.
To evaluate the cumulative childbirth rate after completion of in vitro fertilization (IVF) treatment including three or, in a few cases, four stimulated cycles.
A cohort of 398 couples starting their first IVF treatment between January 1990 and December 1992 were followed until completion of their treatment.
Of 826 started cycles, embryo transfer was performed in 793 cycles, giving a mean of 2.0 completed cycles per couple. In addition, cryopreserved embryos were transferred in 228 cycles (0.57 cycles per couple). 204 couples completed their treatment with delivery or with an ongoing pregnancy, 95 couples underwent three stimulated cycles without achieving an ongoing pregnancy and 66 couples cancelled their treatment after one or two cycles because of varying reasons. In seven women no transfer took place. Twenty-six women have not yet completed their planned cycles. Of 398 couples, where the vast majority had completed their IVF treatment, 51% (204) delivered as a result of the treatment.
IVF treatment combined with freezing of surplus embryos, is a highly effective procedure giving a 'take home baby rate' on a cumulative basis of more than 50% within 1 to 3 cycles.
评估包括三个或少数情况下四个促排卵周期的体外受精（IVF）治疗完成后的累积分娩率。
对1990年1月至1992年12月开始首次IVF治疗的398对夫妇进行队列研究，随访至其治疗结束。
在826个开始的周期中，793个周期进行了胚胎移植，每对夫妇平均完成2.0个周期。此外，228个周期（每对夫妇0.57个周期）移植了冷冻胚胎。204对夫妇完成治疗并分娩或持续妊娠，95对夫妇经历了三个促排卵周期但未实现持续妊娠，66对夫妇因各种原因在一个或两个周期后取消治疗。7名女性未进行移植。26名女性尚未完成计划的周期。在398对夫妇中，绝大多数已完成IVF治疗，其中51%（204对）因治疗而分娩。
IVF治疗结合剩余胚胎冷冻是一种高效的方法，在1至3个周期内累积“带回家婴儿率”超过50%。
