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酮咯酸(痛力克)在术后早期镇痛中的临床应用

[Clinical use of ketorolac (ketrodole) for analgesia in the early postoperative period].

作者信息

Lebedeva R N, Nikoda V V, Petrov R O

出版信息

Anesteziol Reanimatol. 1995 Jan-Feb(1):29-31.

PMID:7605030
Abstract

Ketrodole was administered to 30 patients operated on the abdominal organs, heart and major vessels, lungs and bronchi. The drug was used in a single dose of 30 mg, the maximal daily dose being 90 mg for 16 young patients and 60 mg for 14 elderly patients. Adequate analgesia depending on the time of ketrodole use was attained in 74 to 95% of patients. In 60% of patients with medium intensive pain ketrodole may replace potent opioid analgesics or reduce their daily dose two- or threefold. Ketrodole in the doses used is a relatively safe analgesic.

摘要

对30例接受腹部器官、心脏、大血管、肺和支气管手术的患者使用了酮咯酸。药物采用单次30毫克剂量,16名年轻患者的最大日剂量为90毫克,14名老年患者为60毫克。根据酮咯酸的使用时间,74%至95%的患者获得了充分的镇痛效果。在60%中度疼痛的患者中,酮咯酸可替代强效阿片类镇痛药或使其日剂量减少两至三倍。所用剂量的酮咯酸是一种相对安全的镇痛药。

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