Wheatley R G
Department of Anaesthetics, York District Hospital, England.
Acta Anaesthesiol Belg. 1996;47(3):135-42.
Ketorolac is an efficient drug for the treatment of moderate to severe pain following minor or intermediate types of surgery. Its use is associated with improved quality of recovery, reduced incidence of side effects and earlier discharge from the recovery unit and the hospital in patients treated on an ambulatory basis. With regard to major surgery ketorolac provides insufficient analgesia when administered as the sole agent during the immediate postoperative period. However, it is an effective adjunct to all forms of opioid analgesia being associated with a significant opioid sparing effect. Large scale studies have demonstrated that this combination of improved analgesia and opioid sparing is of clinical benefit.
酮咯酸是一种治疗小型或中型手术后中度至重度疼痛的有效药物。使用该药可改善恢复质量，降低副作用发生率，并使接受门诊治疗的患者更早从恢复室和医院出院。对于大手术，在术后即刻单独使用酮咯酸时镇痛效果不足。然而，它是所有形式阿片类镇痛的有效辅助药物，具有显著的阿片类药物节省效应。大规模研究表明，这种改善镇痛效果和节省阿片类药物的联合应用具有临床益处。
