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产前胎儿心率检测。一、无应激试验的演变

Antepartum fetal heart rate testing. I. Evolution of the nonstress test.

作者信息

Evertson L R, Gauthier R J, Schifrin B S, Paul R H

出版信息

Am J Obstet Gynecol. 1979 Jan 1;133(1):29-33. doi: 10.1016/0002-9378(79)90406-x.

Abstract

On May 1, 1975, at Women's Hospital, Los Angeles County--University of Southern California Medical Center, a new antepartum fetal heart rate (AFHRT) protocol was put into clinical use. This included the widely used contraction stress test (CST) and a new concept of nonstress testing (NST). The NST was based on FHR response associated with fetal movements and was categorized as reactive (normal) or nonreactive (abnormal). The nonreactive fetus was then evaluated with a CST if not contraindicated. During the 24 months, May 1, 1975 to April 30, 1977, a total of 2,422 NST's were done in 1,169 patients with 1,547 (64 per cent) reactive and 829 (35 per cent) nonreactive. CST was done 939 times, with 851 (90.6 per cent) negative, 29 (3 per cent) positive, 13 (1.4 per cent) equivocal, and 46 (5.0 per cent) unsatisfactory. There were ten (3.3 per cent) perinatal deaths within one week of a negative CST, five (1.0 per cent) within one week of a reactive NST, and two (8.7 per cent) with a positive CST. A reactive NST was as predictive of good outcome as was a negative CST. Analysis of the nonreactive NST showed that two or more accelerations were not associated with abnormal CST's. Also, some nonreactive fetuses became reactive with oxytocin and had good outcome. These observations were utilized in the development of a newer, shorter NST which allows for fetal stimulation in an attempt to further define fetal well-being.

摘要

1975年5月1日,在洛杉矶县-南加州大学医学中心的妇女医院,一种新的产前胎儿心率(AFHRT)方案投入临床使用。这包括广泛应用的宫缩应激试验(CST)和一种新的无应激试验(NST)概念。NST基于与胎儿活动相关的胎心率反应,分为反应型(正常)或无反应型(异常)。若无禁忌证,对无反应型胎儿进行CST评估。在1975年5月1日至1977年4月30日的24个月期间,对1169例患者共进行了2422次NST,其中1547次(64%)为反应型,829次(35%)为无反应型。进行了939次CST,其中851次(90.6%)为阴性,29次(3%)为阳性,13次(1.4%)为可疑,46次(5.0%)为不满意。CST阴性后一周内有10例(3.3%)围产期死亡,NST反应型后一周内有5例(1.0%),CST阳性后有2例(8.7%)。NST反应型对良好结局的预测性与CST阴性相同。对无反应型NST的分析表明,两次或更多次加速与异常CST无关。此外,一些无反应型胎儿使用缩宫素后变为反应型且结局良好。这些观察结果被用于开发一种更新、更短的NST,该试验允许对胎儿进行刺激,以进一步确定胎儿的健康状况。

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