Kuhl C K, Kreft B P, Hauswirth A, Gieseke J, Elevelt A, Reiser M, Schild H H
Radiologische Universitätsklinik, Rheinische Fredrich-Wilhelms-Universität Bonn.
Rofo. 1995 Jun;162(6):482-91. doi: 10.1055/s-2007-1015922.
To determine whether medium field strength (0.5 T) MR mammography is able to differentiate between benign and malignant lesions in the same way as a 1.5 T standard technique.
In 40 consecutive female patients with nodular lesions, examinations were carried out at 1.5 T (2D-FFE, TR/TE/FA 200/3.9/80) and 0.5 T (3D-FFE, 24/3.4/40).
There was wide spread of the speed of enhancement of malignant tumours for both techniques (44%-145% with signal increase in the first minute of 42%-189%). In 15 out of 17 carcinomas, the rapidity of uptake and final degree of enhancement after contrast was higher during 0.5 T/3D measurements than it was for 1.5 T/2D images. Fibroadenomas and mastopathies showed similar enhancement characteristics for both techniques. Sharply defined "wash-out" was seen only in malignant lesions; it appeared ten times more frequently in the 0.5 T/3D examinations than at 1.5 T/2D.
The distinction between benign and malignant lesions can be made with more certainty using medium field strength and 3D-FFE sequence than using the 2D high-field standard technique.
确定中场强（0.5T）乳腺磁共振成像是否能够与1.5T标准技术一样鉴别良性和恶性病变。
对40例连续的有结节性病变的女性患者，分别采用1.5T（二维快速场回波序列，重复时间/回波时间/翻转角200/3.9/80）和0.5T（三维快速场回波序列，24/3.4/40）进行检查。
两种技术的恶性肿瘤强化速度范围均较广（第1分钟信号增加44%-145%，42%-189%）。在17例癌中的15例中，0.5T/三维测量时对比剂摄取速度和最终强化程度高于1.5T/二维图像。纤维腺瘤和乳腺病在两种技术下显示出相似的强化特征。仅在恶性病变中可见明显的“廓清”；其在0.5T/三维检查中出现的频率比1.5T/二维检查高10倍。
与二维高场强标准技术相比，使用中场强和三维快速场回波序列能更准确地区分良性和恶性病变。
