Boetes C, Barentsz J O, Mus R D, van der Sluis R F, van Erning L J, Hendriks J H, Holland R, Ruys S H
Department of Diagnostic Radiology, St Radbound University Hospital, Nijmegen, The Netherlands.
Radiology. 1994 Dec;193(3):777-81. doi: 10.1148/radiology.193.3.7972823.
To assess the utility of gadolinium-enhanced dynamic magnetic resonance (MR) imaging with turbo fast low-angle shot (TurboFLASH) technique in the differentiation of benign from malignant lesions of the breast.
Contrast material-enhanced MR images were obtained at intervals of 2.3 seconds for 2 minutes. After the first four images were obtained, contrast medium was intravenously injected within 10 seconds. Lesions that enhanced within 11.5 seconds after the aorta opacified were regarded as malignant. Lesions that enhanced more than 11.5 seconds after the aorta were regarded as benign. A centrifugal pattern of enhancement was regarded as a sign that a lesion was benign.
Eighty-seven lesions were evaluated. Histologic examination showed 65 lesions were malignant and 22 were benign. Gadolinium-enhanced TurboFLASH imaging had a sensitivity of 95%, a specificity of 86%, and an overall accuracy of 93% in differentiating benign from malignant lesions.
Gadolinium-enhanced TurboFLASH imaging is a valuable method in the examination of breast lesions suspected of being malignant.
评估钆增强动态磁共振（MR）成像结合快速低角度激发（TurboFLASH）技术在鉴别乳腺良恶性病变中的应用价值。
以2.3秒的间隔获取对比剂增强的MR图像，持续2分钟。在获取前四张图像后，于10秒内静脉注射对比剂。主动脉显影后11.5秒内强化的病变被视为恶性。主动脉显影后超过11.5秒强化的病变被视为良性。离心式强化模式被视为病变为良性的征象。
共评估了87个病变。组织学检查显示65个病变为恶性，22个为良性。钆增强TurboFLASH成像在鉴别乳腺良恶性病变方面，敏感性为95%，特异性为86%，总体准确率为93%。
钆增强TurboFLASH成像在检查疑似恶性的乳腺病变中是一种有价值的方法。
