1例全身性累及的富于T细胞的B细胞淋巴瘤尸检病例
An autopsied case of T-cell rich B-cell lymphoma with general involvement.
作者信息
Tajima K, Fukase N, Shiono T, Katagiri T, Mito S
机构信息
Department of Internal Medicine, Yamagata Prefectural Kahoku Hospital.
出版信息
Intern Med. 1995 Apr;34(4):243-6. doi: 10.2169/internalmedicine.34.243.
Autoptic findings of a 77-year-old man with T-cell-rich B-cell lymphoma (TCRBCL) showed predominant infiltration of reactive T-cells with a minority population of neoplastic B-cells in liver, spleen, pancreas, adrenal gland, stomach, small intestine and heart, as well as, lymph node. DNA studies demonstrated dual rearrangement in the T-cell receptor beta (TCR beta), immunoglobulin heavy chain J region (IgJH) and kappa light chain J region (IgJ kappa) genes.
一名77岁患有富含T细胞的B细胞淋巴瘤（TCRBCL）男性的尸检结果显示，在肝脏、脾脏、胰腺、肾上腺、胃、小肠、心脏以及淋巴结中，主要是反应性T细胞浸润，伴有少数肿瘤性B细胞。DNA研究表明T细胞受体β（TCRβ）、免疫球蛋白重链J区（IgJH）和κ轻链J区（IgJκ）基因存在双重重排。
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