Hardman A E, Aldred H E
Department of Physical Education, Sports Science and Recreation Management, Loughborough University, UK.
J Cardiovasc Risk. 1995 Feb;2(1):71-8.
The magnitude and duration of the serum triacylglycerol response to a fatty meal may be predictive of coronary artery disease. Exercise can modify this aspect of cardiovascular risk but the effective intensity, duration and timing of exercise is uncertain.
The influence of a single period of walking on the lipaemic response to a high-fat meal (1.2g fat and 71 kj per kilogram body mass) was examined in 12 normolipidaemic young adults (aged 21-33 years, six men and six women). The meal was ingested on two different occasions in a balanced, crossover design. In the control phase, participants rested for 6 h after consuming the meal; in the exercise phase, they walked on a treadmill for 1.5 h at 40% of their maximal oxygen uptake, starting 1.5 h after the meal, and then rested for a further 3 h. Lipid and lipoprotein levels were measured in venous blood taken during the fasted state and at intervals for 6 h after the meal.
The area under the triacylglycerol-time curve was 24 +/- 11% lower during the exercise phase (P < 0.05) than during the control phase because serum triacylglycerol concentrations were lower during recovery from exercise, 3-6 h after the meal.
Prolonged walking starting 1.5 h after the consumption of a fatty meal attenuates postprandial lipaemia in normolipidaemic young adults.
血清三酰甘油对高脂餐反应的幅度和持续时间可能是冠状动脉疾病的预测指标。运动可以改变心血管风险的这一方面，但运动的有效强度、持续时间和时间安排尚不确定。
在12名血脂正常的年轻人（年龄21 - 33岁，6名男性和6名女性）中，研究单次步行对高脂餐（每千克体重1.2克脂肪和71千焦）血脂反应的影响。采用平衡交叉设计，在两个不同的场合摄入该餐。在对照阶段，参与者用餐后休息6小时；在运动阶段，他们在餐后1.5小时开始，以最大摄氧量的40%在跑步机上步行1.5小时，然后再休息3小时。在空腹状态下以及餐后6小时内每隔一段时间采集静脉血，测量血脂和脂蛋白水平。
运动阶段三酰甘油 - 时间曲线下面积比对照阶段低24±11%（P < 0.05），因为餐后3 - 6小时运动恢复期间血清三酰甘油浓度较低。
高脂餐后1.5小时开始的长时间步行可减轻血脂正常的年轻人的餐后血脂异常。
