Kotliarova S E, Krasnova I A, Kovalenko S P
Genetika. 1995 Apr;31(4):573-7.
Frequencies of alleles of the polymorphic locus D17S30 were estimated in a sample of 121 unrelated Siberian inhabitants of European origin. The main method of study was polymerase chain reaction (PCR). The consecutive use of two pairs of primers allowed increasing of the specificity and sensitivity of the amplification reaction. The results of this study may be of theoretical interest for studies in population genetics. They may also find practical application in forensic medical examination and in the diagnosis of some genetic abnormalities.
在121名欧洲血统的西伯利亚非亲属居民样本中,估计了多态性位点D17S30的等位基因频率。主要研究方法是聚合酶链反应(PCR)。连续使用两对引物可提高扩增反应的特异性和灵敏度。这项研究的结果可能在群体遗传学研究中具有理论意义。它们也可能在法医检验和某些遗传异常的诊断中找到实际应用。