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联邦调查局限制性片段长度多态性数据库中独立性检验的比较。

A comparison of tests for independence in the FBI RFLP data bases.

作者信息

Maiste P J, Weir B S

机构信息

Department of Statistics, North Carolina State University, Raleigh 27695-8203, USA.

出版信息

Genetica. 1995;96(1-2):125-38. doi: 10.1007/BF01441158.

Abstract

Several tests of independence of allelic frequencies within and between loci have been compared, and it has been found that Fisher's exact test is the best test to use. When this test is applied to RFLP databases established by the FBI, paying no attention to the single-band problem, there is generally evidence for independence at one locus but not at two loci. When the test is restricted to double-banded entries in the databases; there is overall evidence for independence.

摘要

已经比较了几个关于基因座内和基因座间等位基因频率独立性的检验,并且发现费舍尔精确检验是最适用的检验方法。当将此检验应用于联邦调查局建立的RFLP数据库时,若不考虑单带问题,通常有证据表明一个基因座的等位基因频率是独立的,但两个基因座则不然。当检验仅限于数据库中的双带条目时,总体上有等位基因频率独立的证据。

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