Caproni M, Palleschi G M, Papi C, Fabbri P
Department of Dermatology, University of Florence, Italy.
Int J Dermatol. 1995 May;34(5):357-9. doi: 10.1111/j.1365-4362.1995.tb03619.x.
We describe this case of LEP for its unusual way of presentation. It first appeared with a LEP pattern, followed by a typical DLE of the skin, overlying the nodules only. Moreover, our histologic findings showed the typical pattern of lymphocytic lobular panniculitis, with hyaline necrosis of fat, the lymphoid nodule, and even the lymphocytic nuclear "dust." The epidermal changes, with the liquefaction degeneration of the basal cell layer, a moderate follicular hyperkeratosis, and a perivascular and periappendeal lymphocytic infiltrate, were also observed in the abdominal lesion that developed last without clinically evident DLE.
我们报告这例脂膜炎，因其呈现方式不同寻常。最初表现为脂膜炎样模式，随后仅在结节上方出现典型的皮肤盘状红斑狼疮。此外，我们的组织学发现显示出淋巴细胞性小叶性脂膜炎的典型模式，伴有脂肪透明坏死、淋巴样结节，甚至淋巴细胞核“尘”。在最后出现的腹部病变中也观察到表皮变化，包括基底细胞层液化变性、中度毛囊角化过度以及血管周围和附属器周围淋巴细胞浸润，且该病变无临床明显的盘状红斑狼疮表现。
