去甲肾上腺素和肾上腺素的出现以及雏鸡肠道中它们浓度的发育变化。
The appearance of noradrenaline and adrenaline and the developmental changes in the their concentrations in the gut of the chick.
作者信息
Konaka S, Ohashi H, Okada T, Takewaki T
出版信息
Br J Pharmacol. 1979 Feb;65(2):257-60. doi: 10.1111/j.1476-5381.1979.tb07826.x.
Abstract
- The times of appearance and the concentrations of noradrenaline and adrenaline were determined fluorimetrically in the gut of the embryonic and developing chick. 2. In the duodenum and jejunum, noradrenaline was detected in embryos on the 12th day of incubation. The concentration continued to increase throughout the embryonic stage and attained a maximum within 3 days of hatching. Afterwards, it decreased to about one-third of the peak level. No adrenaline was detectable in most stages of development. 3. In the rectum, noradrenaline was detected in embryos on the 12th day of incubation; both noradrenaline and adrenaline were invariably found on the 15th day of incubation. The concentrations of both amines fluctuated after hatching, but the amount of adrenaline was always approximately 40% of the amount of noradrenaline, except in the adult.
摘要
- 采用荧光法测定了胚胎期和发育期雏鸡肠道中去甲肾上腺素和肾上腺素的出现时间及浓度。2. 在十二指肠和空肠中，孵化第12天的胚胎中检测到了去甲肾上腺素。其浓度在整个胚胎期持续升高，并在孵化后3天内达到最高值。之后，它降至峰值水平的约三分之一。在大多数发育阶段均未检测到肾上腺素。3. 在直肠中，孵化第12天的胚胎中检测到了去甲肾上腺素；孵化第15天总是同时检测到去甲肾上腺素和肾上腺素。孵化后，两种胺类的浓度均有波动，但除成年期外，肾上腺素的量始终约为去甲肾上腺素量的40%。
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