Pournaras C J, Donati G
Clinique Universitaire d'Ophthalmologie, Hôpital Cantonal Universitaire, Genève.
Klin Monbl Augenheilkd. 1995 May;206(5):339-42. doi: 10.1055/s-2008-1035457.
Proliferative vitreoretinopathy (PVR) is defined as the growth and contraction of cellular membranes within the vitreous cavity and on both surfaces of the retina following rhegmatogenous retinal detachment. This process is extremely important as these membranes exert traction and may cause recurrent detachment by reopening otherwise successfully treated retinal breaks or create new retinal breaks. We present the results of a small retrospectively series of 63 cases operated in the University of Geneva Eye Clinic, between 1990 and 1993. Surgical procedure, anatomical results, visual acuity have been reviewed.
Surgical technique, number of surgical procedures, anatomical result and final visual acuity, have been reviewed in each case. Subjects have been divided into two groups depending on the degree of PVR (stage B or C). All patients have been operated combining extra- and intraocular microsurgical technique (scleral buckling, extended vitrectomy, perfluorodecaline, peroperative tamponade, endolaser photocoagulation, retinectomy and gaz or silicone oil tamponade).
In the group presenting a stage-B PVR, the retina was reattached in 79% of cases, but only in 47% of the stage-C cases after one surgical procedure. The functional results showed only 31% of cases with a visual acuity superior to 0.4 in the stage-B group and 28% in the stage-C one. In all the stage-B cases that needed further surgical procedure, the retina could be definitely reattached, but in 9% cases of the stage-C group the retina remained detached and in 18% of the same group permanent silicone oil tamponade was necessary to maintain the retina reattached.
Significant evolution has been observed in microsurgical endoocular surgery in the last ten years, allowing a significant improvement in the anatomical results. Stage-B PVR could be efficiently treated by one surgical procedure in more than 2/3 of cases strongly suggesting the use of endoocular microsurgery as a first intention procedure for retinal detachment complicated by stage-B PVR. An initial stage-C PVR is associated with a poorer anatomical and functional result because of an increased risk of recurrent PVR.
增殖性玻璃体视网膜病变(PVR)的定义是在孔源性视网膜脱离后,玻璃体腔内及视网膜两面的细胞膜生长和收缩。这一过程极为重要,因为这些膜会产生牵引力,可能通过重新打开原本已成功治疗的视网膜裂孔导致视网膜再次脱离,或形成新的视网膜裂孔。我们展示了1990年至1993年间在日内瓦大学眼科诊所进行手术的63例小样本回顾性系列病例的结果。对手术过程、解剖学结果和视力进行了回顾。
回顾了每例患者的手术技术、手术次数、解剖学结果和最终视力。根据PVR的程度(B期或C期)将研究对象分为两组。所有患者均采用眼外和眼内显微手术技术联合进行手术(巩膜扣带术、扩大玻璃体切除术、全氟萘烷、术中填塞、眼内激光光凝、视网膜切除术和气态或硅油填塞)。
在表现为B期PVR的组中,79%的病例视网膜重新附着,但在C期病例中,一次手术后仅47%的病例视网膜重新附着。功能结果显示,B期组中仅有31%的病例视力优于0.4,C期组为28%。在所有需要进一步手术的B期病例中,视网膜最终能够重新附着,但在C期组中,9%的病例视网膜仍脱离,18%的病例需要永久性硅油填塞以维持视网膜附着。
在过去十年中,眼内显微手术有了显著进展,使解剖学结果有了显著改善。超过2/3的病例通过一次手术即可有效治疗B期PVR,这强烈表明眼内显微手术应作为B期PVR合并视网膜脱离的首选手术方法。由于复发性PVR的风险增加,初始为C期的PVR在解剖学和功能结果方面较差。