Ogino S, Kato I, Sakuma A, Takahashi K, Takeyama I, Nakamura T, Kanayama R
Department of Otolaryngology, St. Marianna University School of Medicine, Kanagawa, Japan.
Acta Otolaryngol Suppl. 1995;519:132-5. doi: 10.3109/00016489509121887.
To determine the lesions and the lateralization in patients with Wallenberg's syndrome, visually-guided eye movements were quantitatively analysed and these findings were compared with a lesioned site as revealed by magnetic resonance imaging (MRI). The 8 patients could be clearly classified into two subgroups based on the functional test of eye movements. In 4 patients, optokinetic nystagmus (OKN), pursuit eye movements and fixation-suppression of caloric nystagmus (FS), utilizing the slow phase velocity as a parameter, were impaired toward the lesioned side in the medulla. In the remaining 4 patients, OKN and pursuit eye movements were impaired toward the side contralateral to the lesion, whereas FS toward the lesioned side, indicating a lesion affecting not only the medulla but also the inferior peduncle and/or the cerebellum. Therefore, the functional visually-guided eye movements can provide a useful test battery with which to detect the lesion site in Wallenberg's syndrome.
为了确定延髓背外侧综合征患者的病变及病变侧别，我们对视觉引导下的眼球运动进行了定量分析，并将这些结果与磁共振成像（MRI）显示的病变部位进行了比较。根据眼球运动功能测试，8例患者可明确分为两个亚组。4例患者，以慢相速度为参数，视动性眼震（OKN）、跟踪眼球运动以及热眼震的视固定抑制（FS）向延髓病变侧减弱。其余4例患者，OKN和跟踪眼球运动向病变对侧减弱，而FS向病变侧减弱，提示病变不仅累及延髓，还累及下脚和/或小脑。因此，功能性视觉引导下的眼球运动可为检测延髓背外侧综合征的病变部位提供有用的测试组合。
