Kloth L C
Ostomy Wound Manage. 1995 Jun;41(5):18-20, 22-4, 26-7.
In spite of efforts to create an optimum wound environment for healing, there are times that a wound may not heal, may heal very slowly, or may worsen. In these cases, a series of treatments with an appropriate physical agent can be added to the patient's care plan to augment tissue reparative processes. Three modalities that have received support in the literature for use in wound healing are ultraviolet "C" radiation (UVC), therapeutic heating, and electrical stimulation. Treatment goals for UVC are hyperplasia and enhanced re-epithelialization or desquamation of the leading edge of periulcer epidermal cells, granulation tissue formation, sloughing of necrotic tissue, and bactericidal effects. Treatment goals for therapeutic heating are increased blood perfusion with subsequent increased delivery of oxygen to the tissues (avoiding the dessication of wound tissues). The treatment goal for electrical stimulation is to attract negatively or positively charged cells into the wound area, such as neutrophils, macrophages, epidermal cells and fibroblasts that in turn will contribute to wound healing processes by way of their individual cellular activities.
尽管人们努力为伤口愈合创造最佳环境，但有时伤口可能无法愈合、愈合非常缓慢或会恶化。在这些情况下，可以在患者的护理计划中增加一系列使用适当物理因子的治疗方法，以增强组织修复过程。文献中支持用于伤口愈合的三种治疗方式是紫外线“C”辐射（UVC）、温热疗法和电刺激。UVC的治疗目标是促进增生、增强溃疡周围表皮细胞前沿的再上皮化或脱屑、肉芽组织形成、坏死组织脱落以及杀菌作用。温热疗法的治疗目标是增加血液灌注，随后增加向组织输送氧气（避免伤口组织干燥）。电刺激的治疗目标是将带负电荷或正电荷的细胞吸引到伤口区域，如中性粒细胞、巨噬细胞、表皮细胞和成纤维细胞，这些细胞反过来会通过各自的细胞活动促进伤口愈合过程。
