增殖性糖尿病视网膜病变患者与健康志愿者的眼部血流速度：一项前瞻性研究。
Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study.
作者信息
Mendívil A, Cuartero V, Mendívil M P
机构信息
Ramón y Cajal Hospital, Department of Ophthalmology, Alcalá de Henares University, Madrid, Spain.
出版信息
Br J Ophthalmol. 1995 May;79(5):413-6. doi: 10.1136/bjo.79.5.413.
BACKGROUND
Diabetes affects the vascular ocular circulation. Colour Doppler imaging allows for simultaneous two dimensional anatomical imaging and Doppler evaluation of blood flow velocity; with this technique ocular blood flow velocity can be evaluated in normal and diabetic patients.
METHODS
A prospective study compared blood flow velocity in ocular vessels (ophthalmic artery, posterior ciliary arteries, central retinal vessels, and vortex veins) of 25 patients with proliferative diabetic retinopathy and 30 age matched normal subjects using a colour Doppler imaging unit (Toshiba Sonolayer SSA-270 A with a 5.0 MHz PLF-503 ST phased array scanning head).
RESULTS
The diabetic patients had lower blood velocities than the volunteers. There were significant differences in ophthalmic artery; systolic (p < 0.01), diastolic (p < 0.001), mean velocity (p < 0.05), and central retinal artery; systolic (p < 0.001), diastolic (p < 0.001), mean velocity (p < 0.05). No significant correlations were found between age and blood velocities.
CONCLUSION
Ocular blood flow velocity was decreased in diabetic patients with proliferative diabetic retinopathy.
背景
糖尿病会影响眼部血管循环。彩色多普勒成像可同时进行二维解剖成像以及对血流速度进行多普勒评估；借助该技术，可对正常人和糖尿病患者的眼部血流速度进行评估。
方法
一项前瞻性研究使用彩色多普勒成像设备（东芝Sonolayer SSA - 270 A，配备5.0 MHz PLF - 503 ST相控阵扫描探头），比较了25例增殖性糖尿病视网膜病变患者和30例年龄匹配的正常受试者眼部血管（眼动脉、睫状后动脉、视网膜中央血管和涡静脉）的血流速度。
结果
糖尿病患者的血流速度低于志愿者。眼动脉的收缩期（p < 0.01）、舒张期（p < 0.001）、平均速度（p < 0.05）以及视网膜中央动脉的收缩期（p < 0.001）、舒张期（p < 0.001）、平均速度（p < 0.05）均存在显著差异。未发现年龄与血流速度之间存在显著相关性。
结论
增殖性糖尿病视网膜病变患者的眼部血流速度降低。
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