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持续非卧床腹膜透析中导管内两性霉素B保留治疗真菌性腹膜炎

Intracatheter amphotericin B retention for fungal peritonitis in continuous ambulatory peritoneal dialysis.

作者信息

Lee S H, Chiang S S, Hseih S J, Shen H M

机构信息

Department of Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan R.O.C.

出版信息

J Formos Med Assoc. 1995 Mar;94(3):132-4.

PMID:7613245
Abstract

Two patients who developed fungal peritonitis after receiving continuous ambulatory peritoneal dialysis (CAPD) for various periods were successfully treated with intracatheter retention of amphotericin B and oral flucytosine for 5 weeks. The catheter was not removed and efficient peritoneal permeability was maintained. We suggest that intracatheter retention of antifungal agents to sterilize the catheter along with simultaneous oral antifungal agents be used to eradicate peritoneal infection. The catheter may not need to be removed, and CAPD can be accomplished. The period of hospitalization may, thereby, be shortened, and the efficiency of CAPD can be maintained.

摘要

两名在接受不同时长的持续性非卧床腹膜透析(CAPD)后发生真菌性腹膜炎的患者,通过在导管内留置两性霉素B并口服氟胞嘧啶治疗5周后成功治愈。导管未拔除,且维持了有效的腹膜通透性。我们建议,采用在导管内留置抗真菌药物以使导管无菌,同时口服抗真菌药物的方法来根除腹膜感染。可能无需拔除导管,即可完成CAPD。由此可缩短住院时间,并维持CAPD的有效性。

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