Bosshardt R J, Farwerk R, Sikora R, Sohn M, Jakse G
Clinic of Urology, RWTH Aachen, Germany.
Br J Urol. 1995 Jun;75(6):786-91. doi: 10.1111/j.1464-410x.1995.tb07392.x.
To determine the efficacy and possible beneficial effects of the Catalyst vacuum device (VD) in the treatment of impotence, the ischaemic state of the penis after application of a constriction ring and the origin of the blood in the corpus cavernosum after application of the VD.
Thirty men (mean age 62 years; range 46-76) suffering from erectile dysfunction were selected for the trial after using the VD for 2 weeks at home. Changes in penile tumescence and rigidity before, during and after the VD were assessed using the Rigiscan monitor. Blood gas analysis (BGA) was performed in selected patients whilst using the VD, allowing calculation of the proportional contribution of venous and arterial blood to the increase in penile volume. The efficacy of the VD was also assessed by questionnaires completed before treatment and at the 6 month follow-up.
Four patients were lost to follow-up but the 26 impotent men who used the VD for 6 months were able to have sexual intercourse after using the VD. The average rigidity measured at the base and tip of the penis after application of the VD was > 80%. The duration and extent of nocturnal penile tumescence and rigidity at the start and the end of the study improved, although only one variable increased significantly. Patients reporting spontaneous morning erections showed significant improvements in total erection-time, erection-phase and plateau-phase duration, effective rigidity and tumescence increase. BGA determined 30 min after applying a constriction ring showed ischaemia of the penile blood and the mean contribution of arterial and venous blood to penile blood volume was by 58 and 42%, respectively.
The efficacy of the Catalyst vacuum device was objectively determined and the quality of the nocturnal erections improved in some patients. After application of a constriction ring an ischaemia of the penis developed. In contrast to previous reports, the increased penis volume during the application of the VD is caused not only by arterial inflow but also by venous backflow.
确定催化剂真空装置（VD）治疗阳痿的疗效及可能的有益效果、应用缩窄环后阴茎的缺血状态以及应用VD后海绵体内血液的来源。
30名患有勃起功能障碍的男性（平均年龄62岁；范围46 - 76岁）在家中使用VD两周后入选该试验。使用Rigiscan监测仪评估VD应用前、应用期间及应用后的阴茎肿胀和硬度变化。在部分使用VD的患者中进行血气分析（BGA），从而计算静脉血和动脉血对阴茎体积增加的比例贡献。还通过治疗前及6个月随访时填写的问卷评估VD的疗效。
4名患者失访，但26名使用VD 6个月的阳痿男性在使用VD后能够进行性交。应用VD后阴茎根部和顶端测量的平均硬度>80%。研究开始和结束时夜间阴茎肿胀和硬度的持续时间及程度有所改善，尽管只有一个变量有显著增加。报告有自发晨勃的患者在总勃起时间、勃起期和平台期持续时间、有效硬度及肿胀增加方面有显著改善。应用缩窄环30分钟后进行的BGA显示阴茎血液缺血，动脉血和静脉血对阴茎血容量的平均贡献分别为58%和42%。
客观确定了催化剂真空装置的疗效，部分患者夜间勃起质量有所改善。应用缩窄环后阴茎出现缺血。与先前报道不同，应用VD期间阴茎体积增加不仅由动脉流入引起，还由静脉回流引起。
