Chowhan M A, Asgharian B, Fontana F
Alcon Laboratories Incorporated, Fort Worth, Texas, USA.
Clin Ther. 1995 Mar-Apr;17(2):290-5. doi: 10.1016/0149-2918(95)80027-1.
The comfort of rigid gas-permeable contact lenses is influenced by multiple factors, including the composition of lens material and the presence of surface deposits and/or cleaning solution residues on the lens, as well as the direct effect of lens care solutions on the lens and eye. This study was designed to examine the comparative properties of several soaking solutions with respect to wettability, viscosity, and substantivity, which are essential to maintaining patient comfort. Solutions included in this trial were: OPTI-SOAK Conditioning Solution, Boston Advance Conditioning Solution, Boston Advance Conditioning Solution, Boston Conditioning Solution, Barnes-Hind Wetting and Soaking Solution, Duracare Conditioning, and Total Cleaning, Wetting & Soaking Solution. Wettability, as indicated by mean wetting angle, was determined and OPTI-SOAK Conditioning Solution, followed by Boston Advance and Boston Conditioning solutions, respectively, yielded superior results. For viscosity, OPTI-SOAK Conditioning Solution again provided the most favorable (highest) viscosity, followed by Boston Conditioning and Barnes-Hind solutions. With regard to substantivity, a measure of sustained wettability, Boston Conditioning Solution achieved the highest measurement, followed by OPTI-SOAK and Boston Advance solutions. On the basis of this in vitro evaluation, OPTI-SOAK Conditioning Solution provided the highest potential for patient comfort based on a combination of wettability, viscosity, and substantivity.
硬性透气性隐形眼镜的舒适度受多种因素影响，包括镜片材料的成分、镜片上表面沉积物和/或清洁液残留的存在情况，以及护理液对镜片和眼睛的直接作用。本研究旨在考察几种浸泡液在润湿性、粘度和亲和性方面的比较特性，这些特性对于维持患者舒适度至关重要。本试验所包含的溶液有：OPTI-SOAK护理液、波士顿高级护理液、波士顿高级护理液、波士顿护理液、巴恩斯-欣德湿润与浸泡液、杜拉凯尔护理液以及全效清洁、湿润与浸泡液。通过平均湿润角来测定润湿性，结果显示OPTI-SOAK护理液表现最优，其次是波士顿高级护理液和波士顿护理液。在粘度方面，OPTI-SOAK护理液再次呈现出最适宜（最高）的粘度，其次是波士顿护理液和巴恩斯-欣德溶液。关于亲和性，即持续润湿性的衡量指标，波士顿护理液的测量值最高，其次是OPTI-SOAK护理液和波士顿高级护理液。基于此项体外评估，综合润湿性、粘度和亲和性来看，OPTI-SOAK护理液为患者提供舒适感的潜力最大。
