Castro-Gago M, Cid E, Trabazo S, Pavón P, Camiña F, Rodríguez-Segade S, Einís Puñal J, Rodríguez-Nuñez A
Departamento de Pediatría, Hospital General de Galicia, Clínico-Universitario, Santiago de Compostela, Spain.
Epilepsia. 1995 May;36(5):471-4. doi: 10.1111/j.1528-1157.1995.tb00488.x.
Adenosine monophosphate, inosine monophosphate, inosine, adenosine, guanosine, adenine, guanine, hypoxanthine, xanthine, uric acid, and pyrimidines bases were determined in cerebrospinal fluid (CSF) of 52 children after simple febrile seizures and in a control group of 63 children. There was no statistically significant difference between the two groups for any of these metabolites, suggesting that simple febrile seizures (SFS) neither significantly disturb the metabolism of nucleotides, nucleosides, or bases nor significantly deplete neuron adenosine ATP levels. Therefore, they do not appear to constitute a threat of neuronal damage.
对52名单纯热性惊厥患儿及63名儿童对照组的脑脊液（CSF）进行了检测，测定其中的单磷酸腺苷、单磷酸次黄嘌呤核苷、次黄嘌呤核苷、腺苷、鸟苷、腺嘌呤、鸟嘌呤、次黄嘌呤、黄嘌呤、尿酸及嘧啶碱基。两组间这些代谢物的含量均无统计学显著差异，这表明单纯热性惊厥（SFS）既不会显著干扰核苷酸、核苷或碱基的代谢，也不会显著消耗神经元的腺苷三磷酸（ATP）水平。因此，单纯热性惊厥似乎不会构成神经元损伤的威胁。
