单纯性热性惊厥患儿脑脊液中的嘌呤代谢产物及嘧啶碱基

Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.

作者信息

Rodríguez-Núñez A, Camiña F, Lojo S, Rodríguez-Segade S, Castro-Gago M

机构信息

Departamento de Pediatria, Hospital General de Galician, Clínico Universitario, Santiago de Compostela, Spain.

出版信息

Dev Med Child Neurol. 1991 Oct;33(10):908-11. doi: 10.1111/j.1469-8749.1991.tb14801.x.

DOI:10.1111/j.1469-8749.1991.tb14801.x

PMID:1743415

Abstract

Adenosine monophosphate, inosine monophosphate, inosine, adenosine, guanosine, adenine, guanine, hypoxanthine, xanthine, uric acid and pyrimidine bases were determined in the CSF of 18 children after simple febrile seizures and in a control group. There was no statistically significant difference between the two groups for any of these metabolites. This suggests that simple febrile seizures neither significantly disturb the metabolism of nucleotides, nucleosides or bases, nor significantly deplete neuron adenosine triphosphate ATP levels.

摘要

在18名单纯性热性惊厥患儿及一个对照组的脑脊液中测定了一磷酸腺苷、一磷酸肌苷、肌苷、腺苷、鸟苷、腺嘌呤、鸟嘌呤、次黄嘌呤、黄嘌呤、尿酸和嘧啶碱。两组之间这些代谢物中的任何一种均无统计学显著差异。这表明单纯性热性惊厥既不会显著干扰核苷酸、核苷或碱基的代谢，也不会显著消耗神经元三磷酸腺苷（ATP）水平。