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IR杂种不育增加了黑腹果蝇的重组频率。

IR hybrid dysgenesis increases the frequency of recombination in Drosophila melanogaster.

作者信息

Chaboissier M C, Lemeunier F, Bucheton A

机构信息

Centre de Génétique Moléculaire, CNRS, Gif-sur-Yvette, France.

出版信息

Genet Res. 1995 Jun;65(3):167-74. doi: 10.1017/s0016672300033255.

DOI:10.1017/s0016672300033255
PMID:7615258
Abstract

The I factor is a LINE-like transposable element responsible for the I-R system of hybrid dysgenesis in Drosophila melanogaster. Inducer strains of this species contain several I factors whereas reactive strains do not. I factors are stable in inducer strains, but transpose at high frequency in the germ-line of females, known as SF females, produced by crossing reactive females and inducer males. Various abnormalities occur in SF females, most of which result from this high rate of transposition. We report here that recombination is increased in the germ-line of these females. This is a new characteristic of the I-R system of hybrid dysgenesis that might also be associated with transposition of the I factor.

摘要

I因子是一种类似LINE的转座元件,负责果蝇杂交不育的I-R系统。该物种的诱导品系含有多个I因子,而反应品系则没有。I因子在诱导品系中是稳定的,但在由反应性雌蝇与诱导性雄蝇杂交产生的雌性生殖系(称为SF雌蝇)中高频转座。SF雌蝇会出现各种异常,其中大多数是由这种高转座率导致的。我们在此报告,这些雌蝇的生殖系中重组增加。这是杂交不育I-R系统的一个新特征,可能也与I因子的转座有关。

相似文献

1
IR hybrid dysgenesis increases the frequency of recombination in Drosophila melanogaster.IR杂种不育增加了黑腹果蝇的重组频率。
Genet Res. 1995 Jun;65(3):167-74. doi: 10.1017/s0016672300033255.
2
A genetically tagged, defective I element can be complemented by actively transposing I factors in the germline of I-R dysgenic females in Drosophila melanogaster.一个带有基因标记的缺陷型I因子,可以被黑腹果蝇中I-R杂种不育雌性种系中活跃转座的I因子所互补。
Mol Gen Genet. 1995 Aug 30;248(4):434-8. doi: 10.1007/BF02191643.
3
Transposable and nontransposable elements similar to the I factor involved in inducer-reactive (IR) hybrid dysgenesis in Drosophila melanogaster coexist in various Drosophila species.与果蝇中诱导反应性(IR)杂种不育所涉及的I因子相似的转座和非转座元件共存于多种果蝇物种中。
Proc Natl Acad Sci U S A. 1988 Feb;85(4):1141-5. doi: 10.1073/pnas.85.4.1141.
4
Properties of transgenic strains of Drosophila melanogaster containing I transposable elements from Drosophila teissieri.含有来自蒂氏果蝇I类转座因子的黑腹果蝇转基因品系的特性
Genet Res. 1993 Apr;61(2):81-90. doi: 10.1017/s0016672300031177.
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The P cytotype in Drosophila melanogaster: a maternally transmitted regulatory state of the germ line associated with telomeric P elements.黑腹果蝇中的P细胞型:一种与端粒P元件相关的种系母系传递调控状态。
Genetics. 2004 Jan;166(1):243-54. doi: 10.1534/genetics.166.1.243.
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P-M hybrid dysgenesis does not mobilize other transposable element families in D. melanogaster.P-M杂种不育现象不会激活黑腹果蝇中的其他转座因子家族。
Nature. 1988 Jan 28;331(6154):368-70. doi: 10.1038/331368a0.
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Germ-line and somatic recombination induced by in vitro modified P elements in Drosophila melanogaster.体外修饰的P因子在黑腹果蝇中诱导的种系和体细胞重组。
Genetics. 1990 Feb;124(2):331-7. doi: 10.1093/genetics/124.2.331.
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A long interspersed repetitive element--the I factor of Drosophila teissieri--is able to transpose in different Drosophila species.一种长散在重复元件——果蝇特西埃里氏果蝇的I因子——能够在不同的果蝇物种中进行转座。
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Transposase titration in Drosophila melanogaster: a model of cytotype in the P-M system of hybrid dysgenesis.黑腹果蝇中转座酶滴定:杂种不育P-M系统中细胞型的一个模型
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Identification of a potential RNA intermediate for transposition of the LINE-like element I factor in Drosophila melanogaster.果蝇中类LINE元件I因子转座潜在RNA中间体的鉴定。
EMBO J. 1990 Nov;9(11):3557-63. doi: 10.1002/j.1460-2075.1990.tb07566.x.

引用本文的文献

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Hybrid dysgenesis in results in clusters of mitotic recombination and loss-of-heterozygosity but leaves meiotic recombination unaltered.杂交发育异常会导致有丝分裂重组簇和杂合性缺失,但减数分裂重组不受影响。
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Specific activation of an I-like element in Drosophila interspecific hybrids.果蝇种间杂种中一个类I元件的特异性激活。
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The human LINE-1 retrotransposon creates DNA double-strand breaks.
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