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胰腺坏死(作者译)

[Necrosis of the pancreas (author's transl)].

作者信息

Höfler H

出版信息

Dtsch Med Wochenschr. 1979 Mar 2;104(9):315-7. doi: 10.1055/s-0028-1103903.

Abstract

In a retrospective study, based on 35 392 necropsies, 270 cases of severe acute pancreatitis (stage II or III) were compared with respect to diagnosis, survival time and cause of death. The proportion of correct clinical diagnoses made during life was 29.5% in cases of acute pancreatitis stage II, and 64.1% in severe acute pancreatitis stage III. The average survival time was 13 days. The most common cause of death was shock and intoxication. Most of the deaths in the first phase of the disease were due to pancreatogenic shock and enzyme intoxication. The considerable absorption of toxins from the necrotic tissue becomes a threat to life only after the first week of illness. There was a significant reduction in death rate on the sixth and seventh day of illness: the period from the fifth to seventh day of illness is, therefore, suggested as a most favourable time for any resection of necrotic pancreas tissue.

摘要

在一项基于35392例尸检的回顾性研究中,对270例重症急性胰腺炎(II期或III期)患者的诊断、生存时间和死亡原因进行了比较。II期急性胰腺炎患者生前做出正确临床诊断的比例为29.5%,III期重症急性胰腺炎患者为64.1%。平均生存时间为13天。最常见的死亡原因是休克和中毒。疾病第一阶段的大多数死亡是由于胰腺源性休克和酶中毒。只有在患病第一周后,坏死组织中大量毒素的吸收才会对生命构成威胁。在患病第六天和第七天死亡率显著降低:因此,建议将患病第五天至第七天这段时间作为切除坏死胰腺组织的最有利时机。

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