Gevenois P A, Zanen J, de Maertelaer V, De Vuyst P, Dumortier P, Yernault J C
Department of Radiology, Hôpital Erasme, Brussels, Belgium.
J Clin Pathol. 1995 Apr;48(4):318-22. doi: 10.1136/jcp.48.4.318.
To propose a computerised image analysis based method for measuring, on paper mounted lung sections, the area macroscopically occupied by emphysema.
The study was based on the assessment of 69 lung sections prepared following a modified Gough-Wentworth technique. The results obtained from image analysis, point counting, and panel grading methods were compared, as was the repeatability of image analysis and panel grading.
The results from image analysis and from point counting were not significantly different (p = 0.609) and significant quadratic regressions (r = 0.96, p < 0.001) were found between measurements from image analysis and from panel grading, the computerised technique being shown to be the most reproducible.
Image analysis is a valuable and reproducible method to measure the area of lung macroscopically involved by emphysema.
提出一种基于计算机图像分析的方法，用于测量贴在纸上的肺切片上肉眼可见的肺气肿占据面积。
本研究基于对按照改良的戈夫 - 温特沃斯技术制备的69个肺切片的评估。比较了图像分析、点计数和专家组评分法所获得的结果，以及图像分析和专家组评分的可重复性。
图像分析和点计数的结果无显著差异（p = 0.609），并且在图像分析测量结果和专家组评分之间发现了显著的二次回归（r = 0.96，p < 0.001），计算机技术显示出最高的可重复性。
图像分析是一种有价值且可重复的方法，用于测量肉眼可见的肺气肿累及的肺面积。
