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宫颈上皮内瘤变的分布:子宫切除标本的取材是否恰当?

Distribution of cervical intraepithelial neoplasia: are hysterectomy specimens sampled appropriately?

作者信息

Heatley M

机构信息

Department of Pathology, University of Sheffield Medical School.

出版信息

J Clin Pathol. 1995 Apr;48(4):323-4. doi: 10.1136/jcp.48.4.323.

Abstract

AIM

To determine whether sampling the anterior and posterior cervical lips in hysterectomy specimens provides the best opportunity for detecting unsuspected cervical intraepithelial neoplasia (CIN).

METHODS

The frequency with which CIN was identified at a range of positions on the anterior and posterior lips and left and right lateral aspects of the cervix was assessed in 100 cone biopsy specimens.

RESULTS

CIN affected one or other cervical lip in all 100 cases studied and involved the midline positions (12 and 6 o'clock) in 94. The lateral edges of the cervical canal were also involved in 38 cases.

CONCLUSION

CIN is more likely to be identified on the anterior and posterior lips than on the lateral aspect of the cervical os. The findings support the continuation of the established practice of taking blocks from the midline in these areas.

摘要

目的

确定在子宫切除标本中对宫颈前后唇进行取材是否能为检测未被怀疑的宫颈上皮内瘤变(CIN)提供最佳机会。

方法

在100例锥形活检标本中评估宫颈前后唇及宫颈左右侧不同位置发现CIN的频率。

结果

在所有100例研究病例中,CIN累及一侧或双侧宫颈唇,94例累及中线位置(12点和6点)。38例宫颈管侧缘也受累。

结论

CIN更可能在宫颈前后唇而非宫颈外口侧面被发现。这些发现支持在这些区域继续从中线取材的既定做法。

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引用本文的文献

本文引用的文献

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COLPOMICROSCOPIC STUDIES OF THE DISTRIBUTION OF DYSPLASIA AND CARCINOMA IN SITU ON THE EXPOSED PORTION OF THE HUMAN UTERINE CERVIX.
Cancer. 1965 Aug;18:950-4. doi: 10.1002/1097-0142(196508)18:8<950::aid-cncr2820180805>3.0.co;2-t.
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Histological topography of carcinoma in situ of the cervix uteri.
Cancer. 1959 Mar-Apr;12(2):263-77. doi: 10.1002/1097-0142(195903/04)12:2<263::aid-cncr2820120210>3.0.co;2-r.
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Microinvasive carcinoma of the uterine cervix.子宫颈微浸润癌
Am J Clin Pathol. 1969 Nov;52(5):511-29. doi: 10.1093/ajcp/52.5.511.
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Current views on cervical intraepithelial neoplasia.关于宫颈上皮内瘤变的当前观点。
J Clin Pathol. 1991 Dec;44(12):969-78. doi: 10.1136/jcp.44.12.969.

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