Wu Y, Datta P
Department of Biological Chemistry, The University of Michigan, Ann Arbor 48109-0606, USA.
Mol Gen Genet. 1995 Jun 25;247(6):764-7. doi: 10.1007/BF00290409.
TdcB activity expressed from the chromosomal gene and LacZ expression from single-copy tdc-lacZ transcriptional and translational fusions were measured in Escherichia coli strains harboring mutations in the genes encoding DNA gyrase, topoisomerase I and the HU protein. The pattern of tdc operon expression in these mutants suggests that relaxation of supercoiled DNA enhances tdc transcription in vivo.
