Nissen E, Lilja G, Widström A M, Uvnäs-Moberg K
Department of Woman and Child Health, Karolinska Institute, Stockholm, Sweden.
Acta Obstet Gynecol Scand. 1995 Aug;74(7):530-3. doi: 10.3109/00016349509024384.
The aim of this study was to determine plasma levels of oxytocin in women immediately after delivery.
Oxytocin was measured in 18 healthy women at 15 minute intervals after normal vaginal deliveries with healthy infants. The mothers had their infants put skin-to-skin on their chests immediately after birth. The infants stayed there up to two hours post partum.
There were significant elevations of oxytocin 15, 30 and 45 minutes after delivery (p = 0.007, 0.02 and 0.02 respectively) when compared with average pre partum levels sampled approximately 7-15 minutes before partus. This elevation of oxytocin coincided with the expulsion of placenta. In most women this first elevation was followed by repeated elevations of oxytocin. Oxytocin levels returned to pre partum levels at 60 minutes post partum.
Oxytocin is known to play a role in maternal bonding in animals. Earlier studies indicate that there is a sensitive period for bonding the first hour after giving birth even in women. Our study demonstrates a coincidence of this putative 'sensitive period' and high levels of oxytocin.
本研究的目的是测定女性分娩后即刻的血浆催产素水平。
对18名健康女性在正常阴道分娩出健康婴儿后每隔15分钟测量一次催产素。母亲在婴儿出生后立即让婴儿皮肤贴皮肤地趴在自己胸前。婴儿在产后持续趴在那里长达两小时。
与分娩前约7 - 15分钟采集的产前平均水平相比，分娩后15、30和45分钟时催产素水平显著升高（分别为p = 0.007、0.02和0.02）。催产素的这种升高与胎盘排出同时发生。在大多数女性中，这种首次升高之后是催产素的反复升高。催产素水平在产后60分钟时恢复到产前水平。
已知催产素在动物的母婴联结中起作用。早期研究表明，即使在女性中，分娩后的第一个小时也是母婴联结的敏感期。我们的研究证明了这个假定的“敏感期”与高催产素水平的巧合。
