Kimme-Smith C, Aberle D R, Sayre J W, Hart E M, Greaves S M, Brown K, Young D A, Deseran M D, Johnson T, Johnson S L
Department of Radiological Sciences, University of California at Los Angeles School of Medicine 90095-1721, USA.
AJR Am J Roentgenol. 1995 Aug;165(2):269-73. doi: 10.2214/ajr.165.2.7618538.
Radiographic exposure has been thought to have little impact on the diagnostic quality of chest computed radiography because of automatic digital control of global optical density. The objectives of this study were to compare images obtained with two different exposures in computed radiography with conventional and asymmetric screen-film images of the chest for the detection of simulated lung nodules by use of receiver operating characteristic analysis and to relate differences in observer performance to parameters of image noise measured for each receptor condition.
At 110 kVp (fixed), exposures for the two screen-film systems were those necessary to achieve adequate optical densities over the lung and mediastinal regions of an anthropomorphic phantom. The two exposures used for the computed radiographs corresponded to the exposure used for the conventional chest screen-film system and an exposure 22% lower. An anthropomorphic phantom constructed of materials matched to the muscle, lung, and bone attenuation of a muscular adult man was used. Soft-tissue-equivalent plastic nodules of various sizes were secured at multiple sites on the phantom to simulate lung nodules. The chest phantom was imaged in 50 configurations with a total of 70 superimposed nodules. The perceptual performances of five radiologists were compared by use of receiver operating characteristic analysis. The signal-to-noise ratio in the mediastinum and the coefficient of variation of noise were measured for all four image conditions by use of a step wedge technique to provide an explanation for differences in diagnostic accuracy.
We found no significant differences in the detection of lung nodules between the two screen-film systems or between the conventional screen-film images and the standard-exposure computed radiographs. However, there was a significant decrease in nodule detection on computed radiographs obtained at a reduced exposure; this result was associated with a 21% decrease in the signal-to-noise ratio.
Our results show that underexposure of computed radiographs decreases the detection of low-contrast objects such as lung nodules. Although consistent global optical density on computed radiographs is achieved over a wide range of exposures, the alterations in signal-to-noise ratio that result from underexposure can reduce the diagnostic quality of computed radiographs.
由于全局光学密度的自动数字控制,人们一直认为X线摄影曝光对胸部计算机X线摄影的诊断质量影响不大。本研究的目的是通过使用接收者操作特征分析,比较计算机X线摄影中两种不同曝光条件下获得的图像与胸部传统及非对称屏-片图像,以检测模拟肺结节,并将观察者表现的差异与每种受体条件下测量的图像噪声参数相关联。
在110 kVp(固定)条件下,两种屏-片系统的曝光量是在模拟人体模型的肺部和纵隔区域获得足够光学密度所需的曝光量。用于计算机X线摄影的两种曝光量分别对应于传统胸部屏-片系统所用的曝光量以及低22%的曝光量。使用由与肌肉发达的成年男性的肌肉、肺和骨骼衰减相匹配的材料构建的模拟人体模型。将各种大小的软组织等效塑料结节固定在模型的多个部位以模拟肺结节。胸部模型以50种配置成像,共有70个叠加的结节。通过使用接收者操作特征分析比较了五位放射科医生的感知表现。通过使用阶梯楔形技术测量了所有四种图像条件下纵隔中的信噪比和噪声变异系数,以解释诊断准确性的差异。
我们发现两种屏-片系统之间、传统屏-片图像与标准曝光计算机X线摄影之间在肺结节检测方面没有显著差异。然而,在降低曝光量获得的计算机X线摄影上,结节检测有显著下降;这一结果与信噪比下降21%相关。
我们的结果表明,计算机X线摄影曝光不足会降低对低对比度物体(如肺结节)的检测。尽管在广泛的曝光范围内计算机X线摄影能实现一致的全局光学密度,但曝光不足导致的信噪比改变会降低计算机X线摄影的诊断质量。