Traast H S, Kalkman C J
Department of Anesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands.
Anesth Analg. 1995 Aug;81(2):366-71. doi: 10.1097/00000539-199508000-00027.
We recorded the electroencephalogram (EEG) in 16 patients during propofol/sufentanil total intravenous anesthesia to determine whether EEG changes might predict imminent awakening during emergence. Changes in absolute and relative power in four frequency bands, median frequency (MF), 95th percentile frequency (F95), and two frequency band power ratios (beta/alpha and (alpha+beta)/delta) were quantified. One minute before eye opening, absolute power in the delta and alpha bands had decreased to 49% (25%-73%) and 42% (25%-58%) of the value during the infusion (P > 0.005). MF, F95, and the two frequency band power ratios increased during emergence (P > 0.05). Of the individual spectral variables, only a 50% decrease in absolute alpha power was more than 90% sensitive and specific in predicting eye opening. We conclude that, although pronounced EEG changes occur during emergence from propofol/sufentanil anesthesia, the EEG does not reliably predict eye opening.
我们在16例患者丙泊酚/舒芬太尼全静脉麻醉期间记录脑电图（EEG），以确定EEG变化是否可预测苏醒期即将苏醒。对四个频段的绝对功率和相对功率变化、中位频率（MF）、第95百分位数频率（F95）以及两个频段功率比（β/α和（α+β）/δ）进行了量化。睁眼前1分钟，δ和α频段的绝对功率降至输注期间值的49%（25%-73%）和42%（25%-58%）（P>0.005）。MF、F95以及两个频段功率比在苏醒期增加（P>0.05）。在各个频谱变量中，只有绝对α功率降低50%对预测睁眼的敏感性和特异性超过90%。我们得出结论，虽然丙泊酚/舒芬太尼麻醉苏醒期会出现明显的EEG变化，但EEG并不能可靠地预测睁眼。
