Graham L D, Roe S M
Department of Surgery, Chattanooga Unit, University of Tennessee College of Medicine, USA.
Am Surg. 1995 Aug;61(8):732-4.
Clinically detectable thyroid cancer metastatic to the kidney is rare, with only six cases reported in the medical literature. Four of these have been follicular carcinoma, one papillary carcinoma, and one described as a thyroid adenoma. All of these had known thyroid neoplasms prior to development of their renal metastases. We report herein a seventh case of thyroid carcinoma metastatic to the kidney, unique in that the diagnosis of the kidney metastasis preceded the knowledge of the primary thyroid neoplasm. Furthermore, the follicular variant of papillary cancer, present in this case, has not been previously described in renal metastases from thyroid cancer. Treatment of the kidney metastases led to the subsequent discovery and treatment of the primary thyroid cancer. The patient underwent nephrectomy followed by total thyroidectomy, and is alive and disease-free 3 years postoperatively. Thyroid cancer metastatic to the kidney is rare clinically, but can be amenable to treatment with good long term results.
临床上可检测到的甲状腺癌转移至肾脏的情况罕见，医学文献中仅报道过6例。其中4例为滤泡癌，1例为乳头状癌，1例被描述为甲状腺腺瘤。所有这些病例在发生肾转移之前均已知患有甲状腺肿瘤。我们在此报告第7例甲状腺癌转移至肾脏的病例，其独特之处在于肾转移的诊断先于原发性甲状腺肿瘤的确诊。此外，该病例中存在的乳头状癌滤泡变体，此前在甲状腺癌肾转移中尚未有过描述。对肾转移灶的治疗导致随后发现并治疗了原发性甲状腺癌。患者接受了肾切除术，随后进行了甲状腺全切术，术后3年仍存活且无疾病。甲状腺癌转移至肾脏在临床上罕见，但可通过治疗获得良好的长期效果。
