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Appl Environ Microbiol. 1995 Jul;61(7):2762-4. doi: 10.1128/aem.61.7.2762-2764.1995.
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Thermal adaptation analyzed by comparison of protein sequences from mesophilic and extremely thermophilic Methanococcus species.通过比较嗜温型和超嗜热型甲烷球菌属物种的蛋白质序列来分析热适应性。
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2
Methanococcus igneus sp. nov., a novel hyperthermophilic methanogen from a shallow submarine hydrothermal system.火球菌新种，一种来自浅海海底热液系统的新型嗜热产甲烷菌。
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Enzymes and proteins from organisms that grow near and above 100 degrees C.来自生长在接近100摄氏度及高于100摄氏度环境中的生物体的酶和蛋白质。
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The closed conformation of a highly flexible protein: the structure of E. coli adenylate kinase with bound AMP and AMPPNP.一种高度柔性蛋白质的封闭构象：结合有AMP和AMPPNP的大肠杆菌腺苷酸激酶的结构
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The adenylate kinases from a mesophilic and three thermophilic methanogenic members of the Archaea.古菌中嗜温及三种嗜热产甲烷菌的腺苷酸激酶。
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Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya.迈向生物自然分类系统：关于古菌域、细菌域和真核生物域的提议。
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Protein stability and molecular adaptation to extreme conditions.蛋白质稳定性与分子对极端条件的适应性。
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Di-myo-inositol-1,1'-phosphate: a new inositol phosphate isolated from Pyrococcus woesei.二肌醇-1,1'-磷酸：一种从沃氏嗜热栖热菌中分离出的新型肌醇磷酸。
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压力稳定性并非嗜热酶的普遍特性：沃氏甲烷球菌、泥生甲烷球菌、嗜热栖热甲烷球菌和詹氏甲烷球菌的腺苷酸激酶。

Pressure stabilization is not a general property of thermophilic enzymes: the adenylate kinases of Methanococcus voltae, Methanococcus maripaludis, Methanococcus thermolithotrophicus, and Methanococcus jannaschii.

作者信息

Konisky J, Michels P C, Clark D S

机构信息

Department of Microbiology, University of Illinois, Urbana 61801, USA.

出版信息

Appl Environ Microbiol. 1995 Jul;61(7):2762-4. doi: 10.1128/aem.61.7.2762-2764.1995.

DOI:10.1128/aem.61.7.2762-2764.1995
PMID:7618889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC167549/
Abstract

The application of 50-MPa pressure did not increase the thermostabilities of adenylate kinases purified from four related mesophilic and thermophilic marine methanogens. Thus, while it has been reported that some thermophilic enzymes are stabilized by pressure (D. J. Hei and D. S. Clark, Appl. Environ. Microbiol. 60:932-939, 1994), hyperbaric stabilization is not an intrinsic property of all enzymes from deep-sea thermophiles.

摘要

50兆帕压力的施加并未提高从四种相关嗜温及嗜热海洋产甲烷菌中纯化得到的腺苷酸激酶的热稳定性。因此，尽管已有报道称一些嗜热酶可通过压力实现稳定（D. J. 黑伊和D. S. 克拉克，《应用与环境微生物学》60:932 - 939，1994年），但高压稳定并非所有深海嗜热菌酶的固有特性。