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常规临床护理中糖尿病微量白蛋白尿的筛查:采用哪种方法?

Screening for diabetic microalbuminuria in routine clinical care: which method?

作者信息

Shield J P, Hunt L P, Baum J D, Pennock C A

机构信息

Institute of Child Health, St Michael's Hill, Bristol.

出版信息

Arch Dis Child. 1995 Jun;72(6):524-5. doi: 10.1136/adc.72.6.524.

DOI:10.1136/adc.72.6.524
PMID:7618940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1511129/
Abstract

The measurement of albumin/creatinine ratios and simple albumin concentrations in early morning urine specimens were evaluated to establish which was the best screening test for those likely to have microalbuminuria by the reference standard analysis of timed overnight urine specimens. The measurement of an albumin/creatinine ratio with a cut off of > or = 2.0 mg/mmol was found to be suitable with a specificity of 93% and sensitivity of 97%.

摘要

通过对定时过夜尿液样本的参考标准分析,评估了晨尿样本中白蛋白/肌酐比值和简单白蛋白浓度的测量,以确定哪一项是对可能患有微量白蛋白尿的患者的最佳筛查测试。发现白蛋白/肌酐比值测量值≥2.0 mg/mmol时是合适的,其特异性为93%,敏感性为97%。

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本文引用的文献

1
Diagnostic tests 2: Predictive values.诊断测试2:预测值。
BMJ. 1994 Jul 9;309(6947):102. doi: 10.1136/bmj.309.6947.102.
2
Diagnostic tests. 1: Sensitivity and specificity.诊断测试。1:敏感性和特异性。
BMJ. 1994 Jun 11;308(6943):1552. doi: 10.1136/bmj.308.6943.1552.
3
Angiotensin converting enzyme inhibitor therapy to decrease microalbuminuria in normotensive children with insulin-dependent diabetes mellitus.血管紧张素转换酶抑制剂疗法可降低胰岛素依赖型糖尿病正常血压儿童的微量白蛋白尿。
J Pediatr. 1990 Jul;117(1 Pt 1):39-45. doi: 10.1016/s0022-3476(05)82441-2.
4
Screening for microalbuminuria: which measurement?
Diabet Med. 1991 Oct;8(8):706-11. doi: 10.1111/j.1464-5491.1991.tb01688.x.