Alfaro Monge J M, Soda Merhy A
Departmento de ORL, Instituto Nacional de Enfermedades Respiratorias, M éxico, D. F. M éxico.
Acta Otorrinolaringol Esp. 1995 May-Jun;46(3):187-9.
Little is known about the changes produced in the nasal respiratory epithelium in individuals with an important smoking habit. The purpose of this study is to compare the nasal mucociliary function in healthy subjects, smokers and non-smokers. The nasal mucociliary transport of aspartame particles was measured in 50 healthy non-smokers and in 50 healthy smokers under similar conditions. The average time taken for the displacement of the test substance from the middle third of the inferior turbinate to the oropharynx was found to be in the smokers 13.62 min., and in the non-smokers, 10.34 min. The results were compared using student's "t" test and a significant difference (p < 0.001) was found between both groups. This result is taken as a simple clinical test that evaluates the smoking effects on the nasal mucociliary function.
对于有严重吸烟习惯的个体，其鼻呼吸上皮所产生的变化了解甚少。本研究的目的是比较健康受试者、吸烟者和非吸烟者的鼻黏液纤毛功能。在相似条件下，对50名健康非吸烟者和50名健康吸烟者测量了阿斯巴甜颗粒的鼻黏液纤毛运输。发现测试物质从下鼻甲中三分之一处移动到口咽的平均时间，吸烟者为13.62分钟，非吸烟者为10.34分钟。使用学生“t”检验对结果进行比较，发现两组之间存在显著差异（p < 0.001）。该结果被视为一项评估吸烟对鼻黏液纤毛功能影响的简单临床测试。
