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化疗后副作用的预期与发生情况:恶心和呕吐。

Expectation and occurrence of postchemotherapy side effects: nausea and vomiting.

作者信息

Rhodes V A, Watson P M, McDaniel R W, Hanson B M, Johnson M H

出版信息

Cancer Pract. 1995 Jul-Aug;3(4):247-53.

PMID:7620490
Abstract

Although nausea and vomiting are among the most disruptive chemotherapy side effects, little is known about patients' expectations before therapy and their experience after chemotherapy. A stratified sample of 329 subjects on nine chemotherapy regimens were asked to list their expected symptoms and level of distress. The patients listed a total of 524 responses and 28 different symptoms. This paper focuses on the symptoms of nausea and vomiting. A statistically significant relationship (P = 0.015) was found between the patients' expectations of symptom experience and their expectations of symptom distress. No significant relationship was found between the expectation of the symptom and the actual symptom experience. These findings support the need for educational interventions that provide hopeful but realistic expectations of the unknown events for patients with cancer.

摘要

尽管恶心和呕吐是化疗最具干扰性的副作用,但对于患者在治疗前的期望以及化疗后的经历却知之甚少。对采用九种化疗方案的329名受试者进行分层抽样,要求他们列出预期症状和痛苦程度。患者共列出524份回答和28种不同症状。本文重点关注恶心和呕吐症状。在患者对症状体验的期望与对症状痛苦的期望之间发现了具有统计学意义的关系(P = 0.015)。在症状期望与实际症状体验之间未发现显著关系。这些发现支持了开展教育干预措施的必要性,这些措施要为癌症患者对未知事件提供充满希望但现实的期望

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