Surtees P G
MRC Biostatistics Unit, University Forvie Site, Cambridge.
Br J Psychiatry. 1995 May;166(5):583-94. doi: 10.1192/bjp.166.5.583.
It was proposed to explore the longitudinal relationship between adverse experience and mental health; in particular, whether particular adverse experiences influence the form of subsequent expression of morbidity.
Three groups of women were selected: 64 whose marital partner had recently died, 143 whose husbands had recently experienced a myocardial infarction and a third group of 32 women who had sought protection in a Women's Aid refuge. An initial interview assessed psychiatric status according to the RDC for the six months before the event and up to the time of interview, and a second interview was completed four months after the event had occurred. The course was assessed using the Longitudinal Interval Follow-up Evaluation.
For the coronary group, the prevalence of psychiatric disorder doubled following the experience of the event, and was most pronounced for anxiety disorder. For the bereaved, rates increased over eight times for major depressive disorder and more than twice for anxiety disorder, following the loss; for the refuge group, prevalence rates were lower after entering the refuge than those before. Analyses that took account of the timing of the onset of disorders showed that in almost half of those experienced by the coronary group, and about 40% of the bereaved group, onset pre-dated the timing of the event.
The results further advance knowledge of the evolution and form of psychiatric conditions following the experience of severe adversity.
旨在探讨不良经历与心理健康之间的纵向关系;特别是特定的不良经历是否会影响后续发病表现的形式。
选取三组女性:64名女性的配偶近期去世,143名女性的丈夫近期经历心肌梗死,以及第三组32名在妇女援助避难所寻求庇护的女性。首次访谈根据研究诊断标准(RDC)评估事件发生前六个月直至访谈时的精神状态,事件发生四个月后完成第二次访谈。使用纵向间隔随访评估来评估病程。
对于冠心病组,事件发生后精神障碍患病率翻倍,焦虑症最为明显。对于丧偶组,丧亲后重度抑郁症发病率增加超过八倍,焦虑症发病率增加两倍多;对于避难所组,进入避难所后的患病率低于之前。考虑到疾病发作时间的分析表明,冠心病组近一半患者以及丧偶组约40%患者的发病时间早于事件发生时间。
这些结果进一步推进了对严重逆境后精神疾病演变和形式的认识。