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Individual susceptibility and prevention of occupational diseases: scientific and ethical issues.

作者信息

Van Damme K, Casteleyn L, Heseltine E, Huici A, Sorsa M, van Larebeke N, Vineis P

机构信息

European Trade Union Technical Bureau for Health and Safety, Brussels, Belgium.

出版信息

J Occup Environ Med. 1995 Jan;37(1):91-9. doi: 10.1097/00043764-199501000-00013.

DOI:10.1097/00043764-199501000-00013
PMID:7620948
Abstract

Genetic testing of employees is controversial; objections have been raised with regard to privacy, right to work, and the relevance of the tests. A study is being conducted on "the ethical, social, and scientific problems related to the application of genetic screening and genetic monitoring for employees in the context of a European approach to health and safety at work." A conceptual model is proposed of the complex interactions between exposure, acquired and inherited susceptibility, and risk for disease. The validity of tests for determining genotype and phenotype and their relevance for disease must be evaluated critically to provide an objective basis for ethical discussions. The acceptability of such tests is related to a number of issues, which are identified and discussed.

摘要

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