Mignogna M D, Lo Muzio L, Ruocco V, Bucci E
Department of Oral Pathology, University of Naples Federico II, Faculty of Medicine, School of Dentistry, Italy.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Mar;79(3):295-9. doi: 10.1016/s1079-2104(05)80222-7.
A typical case of Cowden disease is presented. This is rare mucocutaneous disease, genetically determined, with multiple organ system involvement in which a malignancy, particularly of breast and thyroid gland, may develop. The disease can be diagnosed in its early stages by gingival and cutaneous manifestations. We emphasize that the dentist may be the first health care professional who recognizes the syndrome, which is a crucial step to prevent and cure the predictable malignancy.
本文介绍了一例典型的考登病病例。这是一种罕见的遗传性皮肤黏膜疾病，可累及多个器官系统，其中可能会发生恶性肿瘤，尤其是乳腺癌和甲状腺癌。该病在早期可通过牙龈和皮肤表现进行诊断。我们强调，牙医可能是首位识别该综合征的医疗保健专业人员，这是预防和治愈可预见恶性肿瘤的关键一步。
