Cacoub P, Dorent R, Nataf P, Houppe J P, Piette J C, Godeau P, Gandjbakhch I
Eur J Clin Pharmacol. 1995;48(1):81-3. doi: 10.1007/BF00202179.
Appetite suppressants, including aminorex and fenfluramine, have been associated with pulmonary hypertension ever since the well-known outbreak of primary pulmonary hypertension in Europe after treatment with aminorex. The usage of a new anorectic agent, dexfenfluramine, has recently increased dramatically in developed countries. We report 2 new cases of lethal pulmonary hypertension associated with the use of dexfenfluramine.
自使用氨苯恶唑后在欧洲爆发了众所周知的原发性肺动脉高压疫情以来，包括氨苯恶唑和芬氟拉明在内的食欲抑制剂一直与肺动脉高压有关。一种新型食欲抑制剂右芬氟拉明的使用量最近在发达国家急剧增加。我们报告了2例与使用右芬氟拉明相关的致命性肺动脉高压新病例。
