Cloning of the canine interleukin-2-encoding cDNA.

作者信息

Knapp D W, Williams J S, Andrisani O M

机构信息

Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.

出版信息

Gene. 1995 Jul 4;159(2):281-2. doi: 10.1016/0378-1119(95)00078-k.

Here we report the nucleotide sequence of the canine interleukin-2 (IL-2)-encoding cDNA. Cloning of the canine IL-2 cDNA was achieved by the polymerase chain reaction employing, as a template, a cDNA derived from mitogen-stimulated canine splenic lymphocyte mRNA. The deduced amino acid (aa) sequence of canine IL-2 consists of 155 aa and displays 84% sequence similarity to human IL-2.