Barnwell L F, Chaudhuri G, Townsel J G
Department of Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Gene. 1995 Jul 4;159(2):287-8. doi: 10.1016/0378-1119(95)00104-e.
Screening of a human hippocampal cDNA library with a rat creatine transporter cDNA-specific probe revealed two types of clones. One identical to the published creatine transporter cDNA sequence (CRT1) and another (CRT2) with four segments of oligodeoxyribonucleotide substitution or addition in different sites of the CRT1 coding sequence. Translation of the CRT2 coding sequence reveals a new protein with regions of perfect homology with the CRT1 amino-acid sequence.
用人的海马cDNA文库与大鼠肌酸转运体cDNA特异性探针进行筛选，发现了两种类型的克隆。一种与已发表的肌酸转运体cDNA序列（CRT1）相同，另一种（CRT2）在CRT1编码序列的不同位点有四段寡脱氧核糖核苷酸替代或添加。CRT2编码序列的翻译揭示了一种与CRT1氨基酸序列具有完全同源区域的新蛋白质。
