Srivastava P, Arif A J, Pandey V C
Division of Biochemistry, Central Drug Research Institute, Lucknow, India.
Int J Parasitol. 1995 Feb;25(2):203-5. doi: 10.1016/0020-7519(94)00089-7.
Plasmodium berghei infection in Mastomys natalensis impaired the hepatic mitochondrial, microsomal and cytosolic glutathione-S-transferase(s) activity with 1-chloro-2,4-dinitrobenzene as substrate. The enzyme activity was concomitantly decreased with rise in parasitaemia. The decreased enzyme activity due to infection was almost normalized with oral treatment of 16 mg (kg body wt)-1 of chloroquine for 4 days.
